PLX291485

GSE130822: Ascl2-dependent cell differentiation drives regeneration of abated intestinal stem cells

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

Functions of Ascl2 in colonic stem cell maintenance and regeneration. We used RNA-sequencing to profile gene expression in regenerating crypt cells and Ascl2-deficient colonic stem cells, and ASCL2 ChIP-seq to identify transcriptional target genes.; SOURCE: Ramesh Shivdasani (ramesh_shivdasani@dfci.harvard.edu) - Shivdasani Dana Farber Cancer Institute

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