PLX286222

GSE130452: Examining the role of ATRX-RNA interactions in ATRX and PRC2 localization and gene expression.

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We disrupted the RNA binding region in endogenous ATRX and tested localization of ATRX, EZH2 and H3K27me3 by CUT&RUN. We show that ATRX-RNA binding is important to regulate ATRX and PRC2 localization to specific genes. SOURCE: Kavitha Sarma The Wistar Institute

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