PLX092731

GSE129619: Disease modelling of core pre-mRNA splicing factor haploinsufficiency

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We generated a human EFTUD2 knockdown cell line using a CRISPR cas9 nickase strategy to investigate the effects of decreased expression of core spliceosome components on cell characteristics and global transcriptome expression/splicing patterns SOURCE: Huw,Batten,Thomas (huw.thomas@manchester.ac.uk) - Michael Smith Building University of Manchester

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