PLX103310

GSE127459: The Wnt pathway inhibitor, LGK974 has suppressive effects for LPS-induced endotoxemia

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

We demonstrated that Wnt/-catenin pathway was activated in in endotoxemic mice, and the modulation of this pathway by LGK974 had beneficial effects by suppressing the inflammation and lethality caused by endotoxemia. SOURCE: Minwoo Park (mwpark@e-biogen.com) - ebiogen

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