PLX089612

GSE125872: iPS derived microglia like cells cultured with human neurons and astrocytes

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

In this article, Jose Polo and colleagues molecularly compare existing microglia differentiation methods from stem cells, generate a new dual fluorescent and enzymatic reporter tool to study microglia in vitro and in vivo and show that human astrocyte/neuron co-culture pushes the regulatory landscape of in vitro microglia-like cells to more closely resemble bona fide microglia. SOURCE: Jan Schroeder (jan.schroeder@monash.edu) - Epigenetics & Reprogramming Monash University

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