PLX087024

GSE121949: RNA stability profiling in SETD2 and METTL14 knockdown HepG2 cells

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

To evaluate the effect of SETD2 and METTL14 on mRNA stability, we conducted RNA-seq in SETD2 or METTL14 knockdown HepG2 cells as well as control cells with or without actinomycin D treatment. Our RNA stability profiling revealed that depletion of SETD2 and METTL14 resulted in global reduction of RNA stability, and the changes were correlated between SETD2 and METTL14 knockdown cells. SOURCE: Jianjun Chen (jianchen@coh.org) - Chen Lab City of Hope

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