PLX087024

GSE121949: RNA stability profiling in SETD2 and METTL14 knockdown HepG2 cells

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

To evaluate the effect of SETD2 and METTL14 on mRNA stability, we conducted RNA-seq in SETD2 or METTL14 knockdown HepG2 cells as well as control cells with or without actinomycin D treatment. Our RNA stability profiling revealed that depletion of SETD2 and METTL14 resulted in global reduction of RNA stability, and the changes were correlated between SETD2 and METTL14 knockdown cells. SOURCE: Jianjun Chen (jianchen@coh.org) - Chen Lab City of Hope

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