PLX121229

GSE121117: SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

We performed RNA sequencing analysis using NextSeq500 to identify drivers that mediate feedback RAS activation in BRAF(V600E) cells that are SHP2 independent. SOURCE: Ravi Sachidanandam (ravi.mssm@gmail.com) - sachidanandam Icahn School of Medicine at Mount Sinai

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