PLX234558

GSE120337: Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

LncRNA-IIRX plays critical role in Bcr-Abl-induced tumorigenesis. To discover its mechanisms underlying cellular transformation by Bcr-Abl oncogene, genome-wide mRNA expression was measured by RNA-seq in K562 cells expressing shRNA targeting lncRNA-IIRX and control cells. We identified many genes with differential expression in K562 cells after knocking down lncRNA-IIRX. SOURCE: Xuefei Wang (wangxf09sk@126.com) - 1. CAS Key Laboratory of Pathogenic Microbiology and Immunology nstitute of Microbiology, Chinese Academy of Sciences (CAS)

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