PLX085976

GSE119832: The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

The overall goal of this study was to characterize the activity and mechanism(s) of action of the pan-Jumonji domain histone demethylase small molecule inhibitor JIB-04 in the pediatric bone and soft tissue cancer Ewing Sarcoma. SOURCE: Kenneth,L,Jones (Kenneth.L.Jones@ucdenver.edu) - University of Colorado School of Medicine

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