PLX007349

GSE118945: Myocardial-specific ablation of Jarid2 leads to dilated cardiomyopathy in mice

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Analysis of heart from myocardil specific deletion of Jarid2 by crossing Jarid2 floxed mice with aMHC-Cre mice (Jarid2-aMHC). Jarid2-aMHC mice regult in dilated cardomyopathy and reveal premature death. To identify differentially expressed genes in Jarid2-aMHC hearts, we performed RNA-seq analysis on mutant hearts and control heart at postnatal day 10 (P10) and 7 months of ages (7M). SOURCE: Youngsook Lee (youngsooklee@wisc.edu) - University of Wisconsin-Madison

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