PLX008708

GSE116765: Pleiotropic impact of DNA-PK in cancer and implications to therapeutic strategies

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

DNA-dependent protein kinase catalitic subunit (DNA-PK) is associated with aggressive disease. DNA-PK plays a role in transcriptional regulation of cancer-relevent pathways but it is not well understood. This study uses transcriptomic analyses to understand the transcriptional role of DNA-PK in castration resistent prostate cancer (CRPC) upon DNA-PK inhibition SOURCE: Emanuela Dylgjeri (emanuela.dylgjeri@jefferson.edu) - Karen Knudsen Thomas Jefferson University

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