PLX224743

GSE115099: Transcriptome sequencing of differentially expressed genes in acne inversa (AI) patients with NCSTN mutation and healthy individuals

• Organsim human
• Type RNASEQ
• Target gene
• Project ARCHS4

To elucidate the relationship between NCSTN mutations and familial AI pathogenesis by investigating differential gene expression, we have employed transcriptome sequencing profiling as a discovery platform to identify genes with the potential to be involved in familial AI pathogenesis. Skin biopsies were obtained from the lesions of AI patients with NCSTN mutations . Control skin tissues were obtained from healthy individuals undergoing cosmetic surgery procedures SOURCE: Yanyan He (heyanyan.jsnj@163.com) - hinese Academy of Medical Sciences and Peking Union Medical College