PLX208879

GSE114450: Genetic analyses reveal the signaling and transcriptional mechanisms of stomach stromal stem cell niches. [RNA-Seq]

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We demonstrate the conserved Hh-GLI2-mediated chromatin and transcriptional regulation of both stomach and intestinal stromal stem cell niche signals. Analyses of H3K27ac marks demonstrate GLI2-mediated transcription regulation of stem cell niche signals such as Wnt ligand genes, through enhancers conserved between the stomach and intestine. SOURCE: Tae-Hee Kim The Hospital for Sick Children

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