PLX096511

GSE114051: Discovery of a Drug Candidate for GLIS3-Associated Diabetes

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Through development and use of a minimal component protocol for derivation of late stage pancreatic progenitors and beta-like cells, we compared WT and GLIS3-/- pancreatic cells at different stages and discovered that GLIS3-/- cells show an ectopic activation of TGF-beta signaling. SOURCE: Shuibing Chen (shuibing.chen@gmail.com) - Weill Cornell Medical College

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