PLX118377

GSE111230: Induced pluripotent stem cells of patients with Tetralogy of Fallot reveal transcriptional alterations in cardiomyocyte differentiation

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We generated induced pluripotent stem cells (iPSCs) of two patients with Tetralogy of Fallot (TOF) and three healthy relatives of two unrelated familes. We furhter performed mRNA sequencing of iPSCs (day 0) and derived cardiomyocytes (CMs) at day 15 and 60 of patients and healthy relatives. SOURCE: Silke Sperling (silke.sperling@charite.de) - Cardiovascular Genetics Experimental and Clinical Research Center (ECRC), Charité / MDC for Molecular Medicine

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