PLX121526

GSE109795: Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

This submission comprises RNA-Seq profiling of in vivo differentiated pancreatic beta cells types and primary islet-derived pancreatic beta cell sources. The study reports that re-aggregation of immature beta-like cells (d20Beta) and removal of progenitor cells leads to further maturation in vitro resulting in beta-cells (eBCBeta) that are closer to human primary islet-derived beta-cells(IsletBeta). As a control stem cell derived spheres were dissocated, reassociated and taken through till the end of the protocol (NECBeta). SOURCE: Gopika Nair (Gopika.Nair@ucsf.edu) - Matthias Hebrok UCSF

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