PLX099899

GSE109280: Boosting ATM activity alleviates ageing and extends lifespan in a mouse model of progeria.

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

Protein deacetylase SIRT6 and protein kinase ATM both decline during aging, which are of importance in regualtion of glucose metabolism . To explore the mechnisms of SIRT6 and ATM in glycolysis, we analysed the gene expressions in murine embryonic fibroblast cells generated from wildtype, Sirt6-/-, or Atm-/- mice. SOURCE: Min,Xian,Qian (qmx@szu.edu.cn) - Shenzhen University

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