PLX035409

GSE108406: MDM2 inhibitors reverse the transcriptional effects of DMKG plus B87.

Organsim human
Type RNASEQ
Target gene
Project ARCHS4

We reported for the first time that DMKG plus B87 kills cancer cells through a MDM2-dependent cell death mechanism (unpublished results). Moreover, we demonstrated that this effect is reverted by MDM2 inhibitors. We investigated if this effect is transcriptional. SOURCE: Pierre de la Grange (pierre.delagrange@genosplice.com) - GenoSplice technology

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