PLX271289

GSE107104: Increased expression of immune regulatory mediators independently detects tuberculosis in advanced HIV

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Tuberculosis (TB) is the major cause of death in HIV-infected individuals. However, diagnosis of TB in HIV remains challenging. The aim of this study was to determine the performance of published gene signatures in distinguishing active TB in advanced HIV. We concluded that gene expression of FcGR1A and BATF2, and plasma protein levels of IFN and CXCL10 can singly classify active TB in HIV-infected with advanced HIV. SOURCE: Padmini,n/a,SalgameMedicine Rutgers University

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