PLX069774

GSE102491: c-Maf-dependent transcripts in effector Tregs from Peyer's patches

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

We identify c-Maf as an essential factor regulating adoption of RORgamma t+ and T follicular regulatory phenotypes in effector Tregs. Differential expression analysis demonstrates reduced signatures of both ROR gamma t+ Tregs and T follicular regulatory cells following regulatory T cell-specific c-Maf deletion. SOURCE: Maria Ciofani (maria.ciofani@duke.edu) - Duke University Medical Center

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