PLX092350
GSE101838: Rlim-independent XCI in female embryonic stem cells in vitro
- Organsim mouse
- Type RNASEQ
- Target gene
- Project ARCHS4
The transcriptomes of differentiated and undifferentiated E14 (male), Pgk12.1 (female; WT) and Pgk12.1 with a KO of Rlim (RlimKO) were elucidated and examined for differences in X chromosome inactivation. No significant differences between wt and RlimKO with respect to Xist expression and global X-silencing was detected. Results confirm that Rlim is not required for XCI in female ESCs. SOURCE: Ingolf Bach (ingolf.bach@umassmed.edu) - University of Massachusetts Medical School
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