PLX246113

GSE149008: Analysis of differentially expressed long noncoding RNAs and the associated TFmRNA network in tongue squamous cell carcinoma

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Purpose: The purpose of this study was to identify aberrantly expressed lncRNAs and the associated TFmRNA network in TSCC.; Methods: tongue tumor noncoding and mRNA profiles of tongue squamous cell carcinoma and adjacent noncancerous tissues were generated by deep sequencing, using Illumina HiSeq 4000. ; Results: Using an optimized data analysis workflow. ; Conclusions: we found a profile of dysregulated lncRNAs, TFs and mRNAs that could serve as prospective clinical biomarkers because of their tissue specificity and association with the tumorigenesis and progression of TSCC. SOURCE: mi zhang (zhangmi@fjmu.edu.cn) - Fujian Medical University

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