PLX062050

GSE145746: Integrative omics analyses reveal epigenetic memory in diabetic cells regulating genes associated with kidney dysfunction. [sequencing]

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We report novel epigenetic mechanisms of epigenetic memory and its role in regulation of transporter genes in diabetic renal proximal tubules. We have generated RNA-seq, ATAC-seq and Infinium EPIC methylation array datasets from human primary proximal tubule epithelial cells from non-diabetic healthy controls and from patients with history of Type II Diabetes. SOURCE: Anita Bansal (abansal@coh.org) - City of Hope

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