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PLX033816
GSE139061: Transcriptomic Signatures of Kidney Injury in Human Renal Biopsy Specimens
- Organsim human
- Type RNASEQ
- Target gene
- Project ARCHS4
The pathogenesis and molecular signature of human acute kidney injury (AKI) remain incompletely understood, in part, owing to the heterogeneity of the disease. Further, the link between animal models and human AKI is not well characterized. Transcript expression of AKI in 39 native human renal biopsy samples was compared to 9 reference nephrectomies. These data demonstrate that the molecular signature segregates patients with AKI in spite of similar pathological and clinical phenotyping. Such molecular characterization will offer advantages in categorizing and understanding the underlying pathogenesis of phenotypically complex and heterogeneous forms of AKI. SOURCE: Michael,Thomas,Eadon Indiana University
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