PLX278742

GSE138931: RNA-seq analysis of WT and NCOR1f/f,Cd4Cre naive CD4+ T cells

Organsim mouse
Type RNASEQ
Target gene
Project ARCHS4

The differentiation of nave CD4+ T cells into T helper (Th) subsets is key for a functional immune response and has to be tightly controlled by transcriptional and epigenetic processes. However, the function of cofactors that connect gene-specific transcription factors with repressive chromatin-modifying enzymes in Th cells is yet unknown. Here we determined transcriptional changes in naive CD4+ T cells upon deletion of the cofactor NCOR1. SOURCE: Wilfried Ellmeier (wilfried.ellmeier@meduniwien.ac.at) - Medical University of Vienna

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