PLX160324

GSE73016: Primary human trophoblast from term placenta

• Organsim human
• Type RNASEQ
• Target gene
• Project ARCHS4

We compare two groups of transcriptome profiles. They are 1) primary human trophoblasts (PHT) and 2) syncytiotrophoblast from human pluripotent stem cells. This data set represents the former data set and the latter has been deposited separately at GSE72712. Primary human trophoblasts (PHT) were purified cytotrophoblast populations from whole term placentas and then cultured in vitro. The cytotrophoblasts were cultured for short (9 h) or long (48 h) term that show undifferentiated (PHTu) or differentiated (PHTd) phenotype that led syncytialization, respectively. Transcriptome profiles of PHTu and PHTd were compared with three size fractioned syncytiotrophoblasts and trophoblasts from human pluripotent stem cells that are named ESCd_gt70 (greater than 70 m), ESCd_40-70 (size between 40 and 70 m), ESCd_lt40 (smaller than 40 m) and undifferentiated progenitor (ESCu; see GSE72712). SOURCE: Toshihiko Ezashi (ezashit@missouri.edu) - R.M. Roberts University of Missouri-Columbia