PLX311821

GSE156138: Uniform approach for pathway and gene-set based analysis of heterogeneity in single-cell epigenome and transcriptome profiles

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Representation of single cells in biologically meaningfull terms has potential to improve classical analysis steps as well as give rise to multiple new applications. We have developed UniPath for representation of single-cell expression and open-chromatin profile using pathway enrichment scores. UniPath can also perform pseudo-temporal ordering of single-cells using their pathway enrichment-scores. We analysed several datasets using UniPath. Analysis of atlas of mouse single-cell RNAseq profiles with UniPath revealed surprising but biologically-meaningful convergence of different cell-types from distant organs. SOURCE: Vibhor Kumar (kumarv1@gis.a-star.edu.sg) - Genome Institute of Singapore

View on GEOView in Pluto

Key Features

Enhance your research with our curated data sets and powerful platform features. Pluto Bio makes it simple to find and use the data you need.

Learn More

14K+ Published Experiments

Access an extensive range of curated bioinformatics data sets, including genomic, transcriptomic, and proteomic data.

Easy Data Import

Request imports from GEO or TCGA directly within Pluto Bio. Seamlessly integrate external data sets into your workflow.

Advanced Search Capabilities

Utilize powerful search tools to quickly find the data sets relevant to your research. Filter by type, disease, gene, and more.

Analyze and visualize data for this experiment

Use Pluto's intuitive interface to analyze and visualize data for this experiment. Pluto's platform is equipped with an API & SDKs, making it easy to integrate into your internal bioinformatics processes.

Read about post-pipeline analysis

View QC data and experiment metadata

View quality control data and experiment metadata for this experiment.

Request import of other GEO data

Request imports from GEO or TCGA directly within Pluto Bio.

Chat with our Scientific Insights team