PLX153534
GSE151071: Control of gene expression mRNAN6-methyladenosine in pro-B cells
- Organsim mouse
- Type RNASEQ
- Target gene
- Project ARCHS4
N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNA (mRNA). In mice, loss of METTL14, the key m6A writer component, severely blocks B cell development. In this group of RNA sequencing data, we 1. conducted RNA-seq on WT and METTL14 KO pro-B cells (sample 1-10); 2. performed m6A-seq in WT pro-B cells (sample 11-14) and 3. conducted YTHDF2 RIP -seq in WT pro-B cells (sample 15-18). Our data supported that m6A repressed a group of genes in pro-B cells via its reader YTHDF2. SOURCE: Chuan He (chuanhe@uchicago.edu) - University of Chicago
View on GEOView in PlutoKey Features
Enhance your research with our curated data sets and powerful platform features. Pluto Bio makes it simple to find and use the data you need.
Learn MoreAnalyze and visualize data for this experiment
Use Pluto's intuitive interface to analyze and visualize data for this experiment. Pluto's platform is equipped with an API & SDKs, making it easy to integrate into your internal bioinformatics processes.
Read about post-pipeline analysisView QC data and experiment metadata
View quality control data and experiment metadata for this experiment.
Request import of other GEO data
Request imports from GEO or TCGA directly within Pluto Bio.
Chat with our Scientific Insights team