PLX252151

GSE121589: Dissecting the Individual and Collective Regenerative Behavior of Muscle Stem Cells During Aging

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We utilize an integrative genomics approach (bulk RNA-Seq, ATAC-Seq, single-cell RNA-Seq) to show how Muscle Stem Cells (MuSCs) from distinct age groups (young and aged) are significantly altered during the regenerative response. Transcriptional landscapes of populations and single satellite cells during quiescence, activation, proliferation and differentiation from young and aged mice are profiled; alternate splicing between young and aged MuSCs are compared, and chromatin accessibility is compared. SOURCE: Anna Shcherbina (annashch@stanford.edu) - Kundaje Lab Stanford Unviersity

View on GEOView in Pluto

Key Features

Enhance your research with our curated data sets and powerful platform features. Pluto Bio makes it simple to find and use the data you need.

Learn More

14K+ Published Experiments

Access an extensive range of curated bioinformatics data sets, including genomic, transcriptomic, and proteomic data.

Easy Data Import

Request imports from GEO or TCGA directly within Pluto Bio. Seamlessly integrate external data sets into your workflow.

Advanced Search Capabilities

Utilize powerful search tools to quickly find the data sets relevant to your research. Filter by type, disease, gene, and more.

Analyze and visualize data for this experiment

Use Pluto's intuitive interface to analyze and visualize data for this experiment. Pluto's platform is equipped with an API & SDKs, making it easy to integrate into your internal bioinformatics processes.

Read about post-pipeline analysis

View QC data and experiment metadata

View quality control data and experiment metadata for this experiment.

Request import of other GEO data

Request imports from GEO or TCGA directly within Pluto Bio.

Chat with our Scientific Insights team