Pluto Bioinformatics

GSE98841: Overlap in Signaling through Smoothened and the Heterotrimeric G Protein G13

Bulk RNA sequencing

RNA sequencing is used to compare genes regulated by a constitutively active form of Smoothened, a protein critical to Hedgehog signaling, and a constitutively active form of the alpha subunit of the heterotrimeric G proteins G13, which shares some of the primary actions of Smoothened. SOURCE: David Manning (manning@mail.med.upenn.edu) - University of Pennsylvania