Pluto Bioinformatics

GSE98622: Transcriptome profile of a murine renal bilateral ischemia reperfusion model 2 hours to 12 months post injury

Bulk RNA sequencing

Acute kidney injury (AKI) is associated with an increased risk of chronic kidney disease (CKD). To extend our understanding of renal repair, and its limits, we performed a detailed molecular characterization of a murine ischemia reperfusion injury (IRI) model for 12 months post injury. RNA-seq analysis highlights a cascade of temporal specific gene expression patterns related to tubular injury/repair, fibrosis, innate and adaptive immunity. SOURCE: Jing Liu (jing.liu@med.usc.edu) - Andy McMahon lab University of Southern California