Pluto Bioinformatics

GSE96064: H3K4ox-Mediated Chromatin Condensation Protects Breast Cancer Cells from the DNA Damage Repair Machinery

Bulk RNA sequencing

Using an H3K4ox-specific antibody, we determined that the H3K4ox modification is enriched in triple-negative breast cancer (TNBC) cells compared with luminal breast cancer subtypescorrelating with high LOXL2 levels and, importantly, is found primarily in heterochromatin. SOURCE: Sandra Peiró (speiro@imim.es) - IMIM-Hospital del Mar