Pluto Bioinformatics
GSE156449: Nociceptive nerves regulate haematopoietic stem cell mobilization
Bulk RNA sequencing
Nociceptive neuropeptide CGRP acts directly on HSCs via the its receptor RAMP1/CALCRL, to promote egress by activating Gs/Adenylyl cyclase/cAMP pathway. SOURCE: Paul FrenetteDr. Frenette Albert Einstein College of Medicine