Pluto Bioinformatics

GSE93624: Profiling of Ileal Transcriptome in Pediatric Crohn Disease

Bulk RNA sequencing

We report ileal gene expression at diagnosis in a cohort of 210 treatment-nave patients of pediatric Crohn's disease and 35 non-IBD controls from the RISK study. After three years of follow-up after diagnosis, 27 of the CD patients progressed to complicated disease (B2 and/or B3). We aim to test whether Transcriptional Risk Scores helps to distinguish between patient subgroups, improving the predictive power gained from Genetic Risk Scores. SOURCE: Urko M. Marigorta (urkotxapela@gmail.com) - Gibson Lab Georgia Institute of Technology