In this study, we aim to understand the role of miR-29a in in regulating hPSCs. Identification of the differentially expressed  direct and indirect miR-29a targets and the associated pathways from the RNASeq data delineates gene interactions and networks essential for activated PSCs in pancreatic ductal adenocarcinoma (PDAC) in regulating desmoplasia and tumor-stomal crosstalk, which are crucial mechanisms for PDAC progression. SOURCE: Janaiah Kota (jkota@iu.edu) -  Indiana University School of Medicine

Pluto Bioinformatics

GSE144767: Identification of miR-29a-mediated target transcriptome in human pancreatic stellate cells (hPSCs) using RNAseq approach