Pluto Bioinformatics

GSE106510: T helper cells modulate intestinal stem cell renewal and differentiation

Bulk RNA sequencing

Using single-cell RNA-seq of intestinal epithelial cells we identify surprising expression of MHC class II, which participates in a novel interaction between gut-resident CD4+ T cells and epithelial stem cells, governing the balance between stem cell differentiation and renewal. SOURCE: Adam HaberRegev Lab Broad Institute