Pluto Bioinformatics

GSE150176: scRNAseq of CD45+ cells within PDAC tumors treateted with CD40/ICB

Bulk RNA sequencing

Goal: determine how transcriptome of immune cells within the tumor microenvironment changes as a function of CD40 agonist and/or immune checkpoint blockade (anti-PD-1 AND anti-CTLA-4; "ICB") therapy SOURCE: Austin,P,Huffman (ahuffman@pennmedicine.upenn.edu) - University of Pennsylvania