Pluto Bioinformatics

GSE98469: Transcriptional effects of dominant-negative G784E Smarca4 mutation in mouse embryonic stem cells [RNA-seq]

Bulk RNA sequencing

We investigated transcriptomic effects of a Smarca4 ATPase mutant observed in primary tumors and cancer cell lines. Heterozygous expression of G784E Smarca4 mutant led to transcriptional changes compared to cells expressing only wild-type Smarca4. SOURCE: Courtney HodgesCrabtree Lab Stanford University School of Medicine