Pluto Bioinformatics

GSE80673: Comprehensive transcriptomes of mouse pancreatic islet delta, beta, and alpha cells

Bulk RNA sequencing

Rodent models are widely used to study diabetes. Yet, significant gaps remain in our understanding of mouse islet physiology. We generated comprehensive transcriptomes of mouse delta, beta and alpha cells using two separate triple transgenic mouse models generated for this purpose. This enables systematic comparison across thousands of genes between the three major endocrine cell types of the islets of Langerhans whose principal hormones control nutrient homeostasis. SOURCE: Mark,O.,Huising (mhuising@ucdavis.edu) - Huising lab University of California, Davis