The project was designed to figure out the role of microglia in brain inflammation (EAE model). The first step was to find genes/pathways that are upregulated in the microglia during EAE progress but absent in the infiltrating monocytes. These genes/pathways may provide clues for studying the unique function of microglia in the brain inflammation that is disctinct from the infiltrating monocytes. SOURCE: Dan Littman New York University School of Medicine

Pluto Bioinformatics

GSE133180: Microglia and infiltrating monocytes gene expression profiling during EAE progress