Pluto Bioinformatics

GSE144370: PAF1 Drives Pancreatic Cancer Oncogenesis by Promoting Stemness via PHF5A/DDX3 Sub-complex (RNA-seq)

Bulk RNA sequencing

In this study, we established that PAF1 is critical for pancreatic tumorigenesis, and CSC-driven tumor maintenance because depletion of PAF1 resulted in significantly less tumor burden and reduction in CSC populations. SOURCE: Saswati Karmakar (saswati.karmakar@unmc.edu) - UNMC