Pluto Bioinformatics

GSE100861: Single cell transcriptomics reveal an essential role for Hippo signaling in cell state transitions during cardiac fibroblast development

Bulk RNA sequencing

We usesingle cell RNA-sequencing (Drop-seq) to profile cardiac cells(excluded atria) fromcontrol (Wt1 CreERT2/+; Rosa26mTmG/+)and epicardial-deficient Lats1/2 kinaseembryonic hearts (Wt1 CreERT2/+; Lats1/2 F/F;Rosa26mTmG/+) atE13.5 and E14.5. Each experimental group includes cells sampled from four embryonic hearts. SOURCE: Yang Xiao (xyele2003@gmail.com) - Baylor College of Medicine