Pluto Bioinformatics

GSE93279: RNA sequencing of organoids isolated from pancreatic cancer mouse model KRASG12D; p53R172H; Ptf1a-Cre.

Bulk RNA sequencing

We studied the transcriptomics of pancreatic ductal adenocarcinoma (PDAC) and the role of a splicing factor called SF3B1 in this context. We generated mice that will develop PDAC via an inducible expression of KRASG12D; p53R172H specifically in the pancreas using a Ptf1a-Cre. SOURCE: Cédric Cortijo (cedric.cortijo@biol.ethz.ch) - ETHZ