Pluto Bioinformatics

GSE66551: Nuclear orphan receptor TLX affects gene expression in pancreatic beta cells

Bulk RNA sequencing

Using Illuminas digital gene expression (DGE) system, we investigated the transcriptional response to TLX overexpression in beta cells. Finally, an average of 13,791,918 and 12,476,623 reads of high quality clean tags were obtained from control and TLX-overexpressing beta cells, respectively. Results reveals that overexpression of TLX resulted in suppression of 176 genes by 50%, and also results in 2-fold upregulation of 49 genes. SOURCE: XiaoLi Shi (fll766@163.com) - WuHan University

View this experiment on Pluto Bioinformatics