Pluto Bioinformatics

GSE93293: Determination of Lsd1 function in inguinal white adipose tissue (ingWAT) by global transcriptome analysis

Bulk RNA sequencing

To investigate the role of Lsd1 in ingWAT we crossed mice harboring conditional Lsd1 alleles (Zhu et al., 2014) with the Adipoq-Cre deleter strain (Eguchi et al., 2011), which results in Cre-mediated loss of Lsd1 selectively in adipocytes. Transciptome analysis of ingWAT obtained from control and knock-out mice revealed 727 genes differentially expressed between Lsd1 knock-out and control mice at 6 weeks of age (p-value<10-2). SOURCE: Delphine Duteil (delphine.duteil@uniklinik-freiburg.de) - AG Schüle ZKF, Uniklinik