Pluto Bioinformatics

GSE149184: Novel Inhibitors of the Histone-Methyltransferase DOT1L Show Potent Antileukemic Activity in Patient-derived Xenografts (RNA-seq dataset)

Bulk RNA sequencing

Using 3-end RNA-seq followed by digital gene expression analyses we assessed genes that change expression upon treatment with the DOT1L-methyltransferase inhibitors EPZ5676 and the novel drug "compound 10" SOURCE: Florian Perner (f.perner@googlemail.com) - Armstrong Dana Farber Cancer Institute