Purpose: The goals of this study were to identify preferential gene expression signatures that are unique to telogen skin resident Tregs relative to peripheral Tregs;	Methods: Tregs from telogen skin and SDLNs were purified by cell sorting (using the Treg GFP reporter mouse line Foxp3-DTR/GFP) to generate mRNA transcription profiles.;	Results: Transcriptional profiling revealed a unique Skin treg signature relative to SDLN Tregs;	Conclusion: Our study represents the first detailed analysis of the skin Treg transcriptome. SOURCE: Niwa Ali (niwa.ali@ucsf.edu) - Michael Rosenblum Lab UCSF

Pluto Bioinformatics

GSE76138: Transcriptional profiling of Regulatory T-cells isolated from adult skin and skin draining lymph nodes (SDLNs)