Pluto Bioinformatics

GSE147743: RNA stability measurements in RBMS1 knockdown cells and control cells

Bulk RNA sequencing

In order to identify RBMS1-dependent changes in RNA stability, RBMS1 levels in SW480 breast cancer cells were stably knocked-down using short-hairpin RNAs. The cells were then treated with alpha-amanitin to inhibit transcription, RNA was isolated at 0 and 9 hours post-alpha-amanitin treatment, and the samples were transcriptomically profiled. SOURCE: Hani Goodarzi UCSF