Cryptorchidism is the most common congenital defect in children's genitourinary system. It is one of the risk factors for male infertility and testicular tumors. The occurrence of cryptorchidism is closely related to many factors, and the alteration of genes plays an important role in the occurrence of cryptorchidism. A large number of studies have confirmed that the formation of cryptorchidism is related to the differential expression of genes. Therefore, exploring new differential expression genes of cryptorchidism from the transcriptome level and studying the relationship between susceptibility genes and children with cryptorchidism can provide a new direction for studying the pathogenesis of cryptorchidism. SOURCE: Jianfeng Xu (jxu020293@gmail.com) -  Baylor College of Medicine

Pluto Bioinformatics

GSE149084: Next Generation Sequencing Facilitates Quantitative Analysis of Transcriptomics in children with Cryptorchidism