Purpose: To investigate the role and mechanism of circRNAs in gastric cancer.;	Methods: RNA-seq of ribosomal RNA-depleted total RNA and qRT-PCR were performed to screen differential expressed circRNAs between paired gastric cancer tissues and adjacent normal tissues.;	Results: A total of 57623 distinct circRNAs were identified in these samples, and 35120 of these circRNAs contained at least two independent back-spliced reads in at least two samples. Compared with circBase, we found that there were 29007 matched circRNAs and 28616 novel circRNAs in our study. SOURCE: Mengmeng Jie (jmm_416@126.com) -  Third Military Medical University Xinqiao Hospital

Pluto Bioinformatics

GSE121445: Profiling of circular RNAs in gastric cancer tissues and adjacent normal tissues